CS 681 Advance Topics in Computational Biology
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This course is indended for graduate students and advanced undergraduates who would like to learn more about computational methods for solving fundamental problems related to molecular biology. We will talk about genome repeats, their discovery and evolutionary analysis, genome sequence analysis and motif discovery, in particular regulatory element, transcription factor binding site and non-coding RNA indentificiation and search, topics in structural bioinformatics, in particular novel approaches to ncRNA structure prediction, alignment and interaction prediction, small molecule bioinformatics, in particular topics in functional identification, biomolecular networks, their topological properties, evolution and dynamics and other emerging topics in computational molecular biology. The computational techniques that will be covered are both combinatorial and probabilistic; we will also cover many novel machine learning techniques. Grading will be based on class participation, presentations and a final exam. We will have a number of Problem Based Learning sessions to help students improve their collaborative learning, team building and presentation skills.
Credit units: 3 ECTS Credit units: 7.5.
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